Antibiotic Resistant Bacteria: A Challenge to Modern Medicine by Sadhana Sagar & Shilpa Kaistha & Amar Jyoti Das & Rajesh Kumar

Author:Sadhana Sagar & Shilpa Kaistha & Amar Jyoti Das & Rajesh Kumar
Language: eng
Format: epub
ISBN: 9789811398797
Publisher: Springer Singapore

Recently, a new class of recombination has been observed in which only one insertion sequence is required for the mobilization of genetic element (Toleman et al. 2006), such mobile elements are known as insertion sequence common regions (ISCRs). ISCRs possess terminal sequence oriIS and terIS, to originate and terminate replication, respectively. There are innumerable ISCRs which have been studied more often, sinece they are engaged in conferring antibiotic resistance (Toleman et al. 2006). ISCRs were initially detected as associated sequence of class integrons, since they possess the same sequence region CR (Stock et al. 1993); later on it was designated as ISCRs. ISCRs exhibited similarity to a trios a closely related IS elements such as IS91, IS801 and IS1294 (Garcillan-Bracia et al. 2002; Toleman et al. 2006).

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